pentobarbital will lessen the extent or impact of aripiprazole by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.
pentobarbital will minimize the extent or impact of repaglinide by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.
Stay clear of coadministration of ganaxolone with reasonable or powerful CYP3A4 inducers. If coadministration unavoidable, look at escalating ganaxolone dose; on the other hand, don't exceed optimum everyday dose for body weight.
pentobarbital will decrease the extent or outcome of sildenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Stay clear of or Use Alternate Drug. Potent CYP3A4 inducers are anticipated to induce considerable decreases in sildenafil plasma levels
pentobarbital will minimize the level or impact of levamlodipine by influencing hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will lower the level or impact of ethinylestradiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Keep away from or Use Alternate Drug. The efficacy of hormonal contraceptives may very well be lowered. Use of a nonhormonal contraceptive is recommended.
pentobarbital will lower the extent or effect of elagolix by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.
pentobarbital will minimize the extent or outcome of methylprednisolone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of.
Keep an eye on INR much more commonly if coadministered with inducers of such isoenzymes and adjust warfarin dose if necessary.
pentobarbital will lessen the level or result of diazepam buccal by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. Solid or moderate CYP3A4 inducers may perhaps enhance price of diazepam elimination; hence, efficacy of diazepam can be decreased.
pentobarbital will minimize the extent or result of atazanavir by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Importance Mysterious.
Use an alternative means of contraception or even a backup method when enzyme inducers are made use of with mixed hormonal contraceptives (CHCs), and go on backup contraception more info for 28 days soon after discontinuing enzyme inducer to make sure contraceptive dependability.
With therapeutic doses of TCAs, barbiturates boost metabolism and decrease blood concentrations of TCAs.
pentobarbital will lessen the level or result of pimavanserin by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe. Avoid coadministration if at all possible. Keep an eye on for minimized pimavanserin efficacy. An increase in pimavanserin dosage might be required.